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代谢综合征各组分对无症状高尿酸血症发生痛风的影响

Effects of various components of metabolic syndrome on incident gout in asymptomatic hyperuricemia

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【作者】 张琳闫雅更董凤利孙文广郭晓微

【Author】 ZHANG Lin,YAN Ya-geng,DONG Feng-li,SUN Wen-guang,GUO Xiao-wei(Department of Nutrition,The First Affiliated Hospital of Harbin Medical University,Harbin 150001,China)

【机构】 哈尔滨医科大学附属第一医院营养科

【摘要】 目的比较痛风及无症状高尿酸血症者指标的差异,探讨痛风的危险因素。方法选取本院健康体检人群1 209例中34例痛风患者为病例组,63例无症状高尿酸血症者为对照组。采用单因素及多因素分析方法比较两组研究对象体质指数、腰围、血压、空腹血糖、血甘油三酯及胆固醇等代谢综合征各组分的差异,寻找痛风的危险因素。结果单因素分析结果显示,空腹血糖在痛风组和无症状高尿酸血症组间有统计学意义(P<0.05)。多因素分析结果显示,空腹血糖OR值为3.100,有统计学意义(P<0.05)。结论空腹血糖是无症状高尿酸血症人群发生痛风的危险因素。

【Abstract】 Objective To explore the risk factors for gout by comparing the defenses in metabolic syndrome various components between patients with gout and asymptomatic hyperuricemia.Methods Totally 34 patients with gout were enrolled as trial group and 63 patients with asymptomatic hyperuricemia as control group.Single and multi-factors analysis methods were adopted to analyze the differences in metabolic syndrome various components such as BMI,waistline,blood pressure,fasting blood glucose,triglyceride and cholesterol between the two groups so as to detect the risk factors.Results Single factor analysis results showed that the differences between the two groups in fasting blood glucose showed statistically significance(P<0.05).Logistic regression analysis results showed that OR value of fasting blood glucose was 3.100(P<0.05).Conclusion Fasting blood glucose is a risk factor of incident gout in asymptomatic hyperuricemia.

【基金】 黑龙江省卫生厅医学科研课题(2009092);哈尔滨医科大学附属第一医院院基金项目(Q08-029)
  • 【文献出处】 哈尔滨医科大学学报 ,Journal of Harbin Medical University , 编辑部邮箱 ,2011年06期
  • 【分类号】R589
  • 【被引频次】17
  • 【下载频次】251
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