【摘要】 标题化合物是合成除草剂丙草胺的中间体,以2,6-二乙基苯胺在氢化钠作用下与氯乙基丙基醚单烷基化反应合成。当2,6-二乙基苯胺、2-氯乙基丙基醚和氢化钠的物质的量比为2∶1∶1.2、反应温度120℃、反应时间2 h时,标题化合物产率90%,含量99.2%。更多还原

【Abstract】 2,6-Diethyl-N-(2-propoxyethyl)benzenamine is an intermediate for synthesizing herbicide pretilachlor.This intermediate was synthesized by mono-N-alkylation of 2,6-diethylaniline with 1-(2′-chloroethoxy)propane promoted by sodium hydride.The reaction was carried out at 120 ℃ for 2 h at a molar ratio of n(2,6-diethylaniline)∶n(1-(2′-chloroethoxy)propane)∶n(sodium hydride)=2∶1∶1.2,with the yield and purity of 2,6-diethyl-N-(2-propoxyethyl)benzenamine equating to 90% and 99.2%,respectively.更多还原