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生脉注射液联合化疗对晚期非小细胞肺癌患者生活质量的影响

The Effect on Quality of life to Advanced Stage Non-small Cell Lung Cancer Patient Treated with Shengmai Injection Combined Chemotherapy

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【作者】 陈强松; 陈奕; 杨泽江; 刘俊波; 裴润琼;

【Author】 Chen Qiang-song1, Chen Yi1, Yang Ze-jiang2, Li Jun-bo3, Pei Run-qiong1 Oncology Department of Guangxi Hepu County Hospital,Hepu,Guangxi,China 536100 Oncology Department of Guangxi Lingshan County People’s Hospital,Lingshan,Guangxi,China 535400 Guangxi Guigang City Chinese Hospital,Guigang,Guangxi,China 537100

【机构】 合浦县中医院中西医结合肿瘤科; 灵山县人民医院肿瘤科; 贵港市中医院肿瘤科;

【摘要】 目的:观察生脉注射液联合化疗对晚期非小细胞肺癌患者生活质量的影响。方法:将60例晚期非小细胞肺癌按随机数字表法平均分成2组。对照组30例单纯应用化疗,28 d为1个疗程,根据病情缓解情况确定化疗疗程和时限。治疗组30例在对照组化疗基础上加用生脉注射液治疗,15 d为1疗程,2个疗程评价疗效。观察2组临床症状改善率、生活质量提高稳定率和毒副反应变化。结果:2组临床症状改善率比较,治疗组与对照组总改善率分别为83.3%和60.0%(P<0.05);2组生活质量提高稳定率比较,治疗组与对照组提高稳定率分别为70.0%和50.0%(P<0.05);2组毒副反应比较,治疗组毒副反应发生率明显低于对照组(P<0.05)。结论:生脉注射液联合化疗治疗晚期非小细胞肺癌具有保护骨髓,改善临床症状,减轻毒副反应,提高生活质量,延长生存期等作用。

【Abstract】 Objective : To observe influence of the quality of life of the patients treated with sheng mai injection combination chemotherapy for advanced stage non-small cell lung cancer.Methods: 60 patients with terminal NSCLC were randomly divided into 2 groups.30 cases in pure chemotherapy,every 4 weeks for a cycle,according to the illness ease,determine the chemotherapy regimen and duration.30 cases in control group based on chemotherapy combined with shenmai injection treatment,15 days for 1 course of treatment,2 course of treatment efficacy evaluating.Observe 2 groups of clinical symptoms period,the quality of life,improve active and side-effect of change.Results: Total improving rate of 2 groups were 80.3%,60.0% respectively(P<0.05).2 groups of life quality improving active were 70.0% and 50.0%,respectively(P<0.05).Two groups of adverse reaction compare,adverse reaction rate the treatment group of obviously lower than in control group(P<0.05).Conclusion: Shengmai injection combination chemotherapy treating advanced non-small cell lung cancer with the protection of bone marrow can improve the clinical symptoms,reduce adverse reaction,improve life span and prolong surial functions.

【基金】 广西自治区卫生厅科研课题(编号:Z2010470)
  • 【文献出处】 中医学报 ,China Journal of Chinese Medicine , 编辑部邮箱 ,2011年01期
  • 【分类号】R734.2
  • 【被引频次】7
  • 【下载频次】124
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