Objective: To discuss the technique and effect of hemoperfusion combined with hemodialysis in treating acute and sever poisoning.Methods: A total of 38 cases with acute and sever poisoning which were admitted from Jan 2007 to Dec 2011 were selected and treated by hemoperfusion combined with hemodialysis.And another 34 cases with acute and sever poisoning were selected as control.The efficacy was observed and compared.Results: All 38 cases in treatment group were rescued successfully.The coma duration,averag...