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SCI患者hs-CRP水平和颈动脉粥样硬化的关系

Relationship between serum high-sensitivity C-reactive protein level and carotid atherosclerosis in patients with silent cerebral infarction

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【作者】 马建军孙翠萍朱好辉李学祁亚伟冯艳袁丽品

【Author】 MA Jian-jun1,SUN Cui-ping2,ZHU Hao-hui3,LI Xue1,QI Ya-wei1,FENG Yan1,YUAN Li-pin1 (1.Department of Neurology,Henan Provincial People’s Hospital,Zhengzhou 450003,China;2.Department of Internal Medicine,Henan Tumor Hospital,Zhengzhou 450008,China;3.Department of Ultrasound,Henan Provincial People’s Hospital,Zhengzhou 450003,China)

【机构】 河南省人民医院神经内科河南省肿瘤医院内科河南省人民医院超声诊断科

【摘要】 目的:探讨无症状性脑梗死(SCI)患者血清高敏C反应蛋白(hs-CRP)水平与颈动脉粥样硬化的关系。方法:用免疫散射比浊法测定68例SCI患者和65例健康人血清hs-CRP水平,并对68例SCI患者进行颈动脉彩色多普勒超声检测。结果:SCI血清hs-CRP水平([16.4±4.5)mg/L]高于对照组([10.6±2.7)mg/L(,P<0.01)]。SCI组hs-CRP水平与颈动脉粥样硬化程度(r=0.48,P<0.01)和颈动脉狭窄程度(r=0.51,P<0.05)呈正相关。结论:SCI患者hs-CRP水平与颈动脉粥样硬化有关。

【Abstract】 Objective: To investigate the relationship between serum high-sensitivity C-reactive protein level(hs-CRP) and carocid atherosderosis in patients with silent cerebral infarction(SCI). Methods: The serum hs-CRP levels were measured by immunodiffusion turbidimetry in 68 patients with SCI and 65 healthy controls.Color ultrasonography was used to observe the carotid atherosclerosis and the severity of stenosis of the extracranial carotid in 68 patients with SCI. Results: The serum hs-CRP level in SCI group[(16.4±4.5)mg/L] was significantly higher than that in control group[(10.6±2.7)mg/L(P<0.01)].The serum hs-CRP level was significantly correlated with degrees of carotid atherosclerosis(r=0.48,P<0.01) and severity of stenosis in the extracranial carotid(r=0.51,P<0.05). Conclusion: The serum hs-CRP level in patients with SCI is associated with carotid atherosderosis.

【基金】 河南省医学科技攻关计划项目(201003118)
  • 【文献出处】 河南医学研究 ,Henan Medical Research , 编辑部邮箱 ,2011年04期
  • 【分类号】R743.33
  • 【下载频次】33
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