【摘要】 目的观察钙离子拮抗剂尼莫地平加脑脊液置换对蛛网膜下腔出血的临床预后。方法 74例蛛网膜下腔出血患者分为治疗组38例和照组36例。2组入院后即开始泵入尼莫地平,持续14d;治疗组加脑脊液置换治疗,其他治疗同对照组。观察2组的脑血管痉挛发生率及临床预后。结果治疗组脑血管痉挛及临床预后均较对照组显著好转(P<0.05)。结论尼莫地平加脑脊液置换治疗蛛网膜下腔出血可以有效减少脑血管痉挛及改善预后。更多还原

【Abstract】 Objective To observe the clinical prognosis of nimodipine and cerebrospinal fluid replacement for subarachnoid hemorrhage(SAH).Methods Total 74 patients with SAH were randomly divided into treatment group(38 cases) and control group(36 cases).Nimodipine was pumped continuously into both two groups for 14 days.The treatment group was similar to control group except permutating cerebrospinal fluid.The CVS and clinical prognosis were observed and compared between the two groups by blind trial.Results Compared with control group,CVS was significantly diminished(P<0.05),and clinical prognosis was improved in treatment group.Conclusion Nimodipine and cerebrospinal fluid replacement for subarachnoid hemorrhage(SAH) are proposed to diminish CVS and improve clinical prognosis.更多还原