【摘要】 急性缺血性卒中,是当今社会引起人类死亡和残疾的主要疾病。rt-PA为目前惟一批准用于治疗急性缺血性卒中的药物。然而2,0%～34%的患者在溶栓后发生了再闭塞。而早期再闭塞与远期预后高度相关。本文通过溶栓后再闭塞的发生机制,综述溶栓后早期抗血小板联合抗凝治疗进行神经功能维护的研究进展。更多还原

【Abstract】 Acute ischemic stroke is an important cause of death and the most frequent cause of permanent disability recently.rt-PA is currently the only approved for the treatment of acute ischemic stroke thrombolytic drugs.However,re-occlusion occurs in 20~34% after rt-PA treated and early re-occlusion is highly predictive of long-term poor outcome.This review will discuss the rationale of ischemic stroke and potential therapeutic strategies after thrombolysis and the current situation of early antiplatelet and anticoagulant therapy.更多还原