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第三腰椎横突综合征患者血清SOD和MDA的检测及其临床意义

Detection and Clinical Significance of SOD and MDA in the Serum of Patients with the Third Lumbar Transverse Process Syndrome

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【作者】 鲁世荣赵杨秦晓霖赵健王雷魏巍王春光王广宏

【Author】 LU Shi-rong,ZHAO Yang,QIN Xiao-lin,et al.(Department of Orthopedic Surgery,AVIC Harbin No.242 Hospital,Harbin,150066,China)

【机构】 中航工业哈尔滨二四二医院骨科

【摘要】 目的:探讨第三腰椎横突综合征患者血清中超氧化物歧化酶(serum superoxide dismutase,SOD)的活性及丙二醛(malondialdehyde,MDA)的水平变化与第三腰椎横突综合征发生发展的作用。方法:用分光光度计及硝酸还原酶法测定30例第三腰椎横突综合征治疗前后SOD活性、MDA的水平。结果:第三腰椎横突综合征患者治疗前SOD活性低于治疗后SOD活性(P<0.01);第三腰椎横突综合征患者治疗前MDA的水平高于治疗后的水平(P<0.05)。结论:氧化失衡存在于第三腰椎横突综合征发病中,SOD和MDA可能在第三腰椎横突综合征发生发展中发挥一定的作用。

【Abstract】 Objective:To explore the role by investigating the activity and the level changes of SOD and MDA in the serum of patients with the third lumbar transverse process syndrome.Methods:Using spectrophotometer and nitratereductase technique to measure the serum levels of MDA and the activity of SOD in 30 patients with the third lumbar transverse process syndrome.Results:The activity of SOD before the treatment was significantly lower than those after the treatment(P<0.01).The serum levels of MDA before the treatment significantly higher than those after the treatment(P<0.05).Conclusions:SOD and MDA are indirect sign to reflect the treatment level of the patients with the third lumbar transverse process syndrome.

【基金】 黑龙江省卫生厅科研课题项目:2009-531
  • 【文献出处】 航空航天医学杂志 ,Journal of Aerospace Medicine , 编辑部邮箱 ,2011年10期
  • 【分类号】R681.5
  • 【被引频次】5
  • 【下载频次】61
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