【摘要】 目的:探讨各种浓度高渗盐水对重型颅脑外伤后脑水肿患者,降低颅内压,提高脑灌注压的效果。方法:选择我院160例患者,按照应用高渗盐水的浓度不同,分为四组,每组各40例,持续监测患者平均动脉压、颅内压,比较各组之间对于降低颅内压,提高脑灌注压的效果。结果:7.5%HS组颅内压降低幅度高于另外三组(P<0.05),7.5%HS组平均动脉压明显高于其他三组(P<0.05),7.5%HS组颅内压明显低于其他三组(P<0.05),7.5%HS组患者脑灌注压明显高于其他三组(P<0.05)。结论:四种不同浓度的高渗盐水,在降低脑外伤后脑水肿患者颅内压、提高脑灌注压方面均有一定效果,其中以7.5%HS效果最佳。更多还原

【Abstract】 Objective: To explore the various concentrations of hypertonic saline on brain edema in patients with severe head trauma,increased intracranial pressure,cerebral perfusion pressure.Method: 160 patients,according to the different concentrations of hypertonic saline,were divided into 4 groups,each with 40 cases,continuous monitoring of patients with mean arterial pressure,intracranial pressure,comparing each group to reduce intracranial pressure enhance the effect of cerebral perfusion pressure.Result: 7.5% HS group rate of intracranial pressure was lower than the other three groups(P<0.05),7.5% HS group rate of the average arterial pressure was significantly higher than the other three groups(P<0.05),7.5% HS group rate of intracranial pressure was significantly lower than the other three groups(P<0.05),7.5% HS group rate of cerebral perfusion pressure was significantly higher than the other three groups(P<0.05).Conclusion: Four different concentrations of hypertonic saline can reduce brain edema after traumatic brain injury patients with intracranial pressure,increase cerebral perfusion pressure,but 7.5% HS is the best of all.更多还原