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两种方法治疗膝关节骨关节炎疗效对比观察

Comparison of sodium hyaluronate injection with oral articular cartilage protectants sulfuric acid glucosamine in the treatment of knee osteoarthritis

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【作者】 陈维飞陈文李丽花林松

【Author】 CHEN Wei-fei,CHEN Wen,LI Li-hua,et al. Department of Rheumatology,Hainan Nongken Hospital,Haikou 570311,Hainan,CHINA

【机构】 海南省农垦总医院风湿科海南省农垦总医院骨伤科

【摘要】 目的比较两种方法治疗膝关节骨关节炎的疗效。方法将81例膝关节骨关节炎(OA)患者随机分为两组,分别给予关节腔内注射玻璃酸钠及口服关节软骨保护剂硫酸氨基葡萄糖治疗,随诊一年以上,对关节疼痛、肿胀积液、关节活动度及行走功能综合评分,进行相关性分析。结果关节腔注射玻璃酸钠组患者,治疗后0~6个月关节疼痛、肿胀积液及关节活动度、行走功能均优于口服氨基葡萄糖组患者,治疗后半年至一年半两组患者关节肿胀、疼痛及活动功能差异无统计学意义。结论关节腔注射玻璃酸钠治疗膝关节骨关节炎能够减轻疼痛并改善关节机能,其近期疗效优于口服氨基葡萄糖。

【Abstract】 Objective To compare the efficacy of sodium hyaluronate injection and oral articular cartilage protectants sulfuric acid glucosamine in the treatment of knee osteoarthritis. Methods 81 patients with osteoarthritis were divided randomly into sodium hyaluronate injection group(n=39) and oral articular cartilage protectants sulfuric acid glucosamine group(n=42) for more than one year. Make relevant analysis and comprehensive rating of the joint pain,swelling,and walking function. Results After 0~6 months,the articulatory antrum of sodium hyaluronate injection group was better than that of oral articular cartilage protectants sulfuric acid glucosamine group. After 6~18 months,there was no statistical difference between two groups. Conclusion Articulatory antrum of sodium hyaluronate injection can reduce pain and improve joint function,and its short-term curative effect will surpass the oral glucosamine.

  • 【文献出处】 海南医学 ,Hainan Medical Journal , 编辑部邮箱 ,2011年14期
  • 【分类号】R684.3
  • 【被引频次】8
  • 【下载频次】54
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