节点文献
水介质中吡喃香豆素衍生物的一釜合成
One-pot Synthesis of Pyranocoumarin Derivatives in Aqueous Media
【摘要】 水介质中四丁基溴化铵(TBAB r)催化下,芳香醛、4-羟基香豆素和丙二腈经微波辐射一釜合成了一系列2-氨基-3-氰基-4-芳基-4H-吡喃并[3,2-c]香豆素的衍生物。该方法具有反应时间短,收率高,后处理简便,环境友好等优点。
【Abstract】 A series of 2-amino-3-cyano-4-aryl-4H-pyranocoumarin derivatives were synthesized by the reaction of aromatic aldehyde,4-hydroxycoumarin and malononitrile in aqueous media catalyzed by Tetrabutyl ammonium bromide(TBABr) under microwave irradiation.This method had the advantages of shorter reaction time,high excellent yield,simple work-up,and eco-friendly.
【关键词】 丙二腈;
四丁基溴化铵;
香豆素;
微波;
【Key words】 malononitrile; tetrabutyl ammonium bromide(TBABr); coumarin; microwave;
【Key words】 malononitrile; tetrabutyl ammonium bromide(TBABr); coumarin; microwave;
【基金】 河北省自然科学基金资助课题(B2009000161)
- 【文献出处】 广州化工 ,Guangzhou Chemical Industry , 编辑部邮箱 ,2011年04期
- 【分类号】TQ252.1
- 【被引频次】1
- 【下载频次】157