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多头胆管内支架管植入术在胆囊癌合并黄疸治疗中的作用研究

Utility of the multi-directional biliary stent in patients with obstructive jaundice induced by gallbladder cancer

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【作者】 余伟黄长山王云检崔宏韩风张玲

【Author】 YU Wei HUANG Changshan WANG Yunjian CUI Hong HAN Feng ZHANG Ling Department of Hepatobiliary & Pancreatic Surgery,Henan Tumor Hospital,Zhengzhou 450003,China

【机构】 河南省肿瘤医院肝胆胰外科

【摘要】 目的探讨自制多头胆管内支架管在胆囊癌合并黄疸治疗中的作用。方法对26例胆囊癌合并黄疸患者行自制多头胆管内支架管置入术,术后观察肝功能相关指标变化并进行随访。结果置入自制多头胆管内支架管后,复查患者肝功相关指标,谷丙转氨酶、谷草转氨酶、谷氨酰转肽酶、总胆红素、直接胆红素等均有明显下降;21例获随访患者总体中位生存时间为7个月,最长生存27个月。结论多头胆道内支架管置入术能很好的解除晚期胆囊癌患者的胆道梗阻,明显改善患者生存质量并有效的延长患者生存期。

【Abstract】 Objective To investigate the role of the Multi-directional biliary stent in patients with obstructive jaundice induced by gallbladder cancer.Methods 26 cases of gallbladder carcinoma in patients with jaundice underwent multi-directional biliary stent implantation,postoperative changes in liver function were observed and follow-up was carried out.Results After the operation,serum levels of the alanine aminotransferase,aspartate aminotransferase,glutamyl peptidase,total bilirubin and the direct bilirubin were significantly reduced;21 patients with a median overall survival of 7 months were followed up,the longest survival time was 27 months.Conclusion The Multi-directional biliary stent implantation not only relieve obstructive jaundice in patients with advanced gallbladder,but also improve the quality of life and prolong survival significantly.

  • 【文献出处】 中国医药科学 ,China Medicine and Pharmacy , 编辑部邮箱 ,2011年19期
  • 【分类号】R735.8
  • 【下载频次】33
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