【摘要】 目的了解孕妇和婴幼儿麻疹抗体水平及变化规律。方法随机抽取孕妇采血并在生产时采集脐带血;用分层抽样方法随机抽取8月龄以下、8月龄～、18月龄～3岁共3个年龄组幼儿血;采用酶联免疫吸附试验(ELISA)检测麻疹IgG抗体,对以上5个年龄组麻疹抗体进行分析。结果孕妇麻疹IgG阳性率72.16%,保护率54.64%,几何平均滴度为1∶503。新生儿麻疹IgG阳性率61.86%,保护率35.05%,GMT为1∶305。母婴麻疹抗体的相关系数为0.8571。新生儿麻疹IgG抗体男女差异无显著性意义(P>0.05)。孕妇、新生儿、<8月龄组麻疹IgG抗体低于接种期幼儿。结论孕妇及新生儿麻疹抗体水平偏低,应加强育龄妇女的血清学监测,开展强化免疫。更多还原

【Abstract】 Objective To understand the change of measles antibody level in pregnant women and infants.Methods The serum samples from pregnant women and three age group infants selected randomly.were collected,and tested by the method of ELISA.Antibody levels of different people were compared.Results Positive rate of measles antibody in the pregnant women was 72.16% with a protective rate of 54.64%,Geometric mean titer(GMT) was 1∶503.The positive rate of measles antibody in newborns was 61.86% with a protective rate of 35.05%,and GMT was 1∶305.The correlation coefficient for measles antibody levels in mother and infant was 0.8571.Neonate’s measles IgG antibody levels were no significant difference between two sexes;and the antibody levels in pregnant women,newborns,and infants under 8m-year-old group were lower than those of other groups.Conclusion Positive rate of measles antibody is not high enough in pregnant women and infant.It is considerable to strengthen detecting measles antibody and carry out timely supplementary immunization in pregnant women.更多还原