Polyethylene glycol(PEG)-conjugated vaccine of Vibrio harveyi was made by PEG which was used for ultrasonic carrier and ultrasonic medium,and by the inactivation methods of transient high-temperature,high press and shearing force of ultrasonic.For comparing the difference between two kinds of vaccine,the PEG-conjugated vaccine and traditional vaccine were injected into Cryprinuscarpiod intraperitioneally,respectively,then the percentage of phagocytosis,the index of phagocytosis,antibacterial activities,anti...