【摘要】 目的探讨脑实质内脑膜瘤(Intraparenchymal meningioma)或皮层下脑膜瘤(Subcortical meningioma)的发病规律、发生机理、诊断及治疗。方法回顾性分析了我们治疗的2例及SCI、Medline收录文献中报道的17例脑实质内或皮层下脑膜瘤。结果 19例脑实质内或皮层下脑膜瘤中,男8例,女11例,男女之比为1:1.38;年龄最小1岁,最大73岁,中位数为17岁。首发症状癫痫10例(占52.6%),头痛5例(占26.3%)。除2例没有CT或MRI检查外,17例脑实质内或皮层下脑膜瘤中有7例为囊性脑膜瘤,占41.2%,周围伴有明显水肿者12例,占70.6%,伴有钙化者3例,占17.6%。组织学检查显示WHOI级脑膜瘤15例,占78.9%,其中11例为纤维型,占73.3%。WHOⅡ级脑膜瘤3例,占15.8%,WHOⅢ级脑膜瘤1例,占5.3%。结论脑实质内或皮层下脑膜瘤男性发生率高于一般脑膜瘤,发病年龄较小,最常见的首发症状为癫痫,囊性脑膜瘤发生率高,WHOI级脑膜瘤中绝大多数为纤维型,WHOⅡ、Ⅲ级脑膜瘤发生率高于一般脑膜瘤。更多还原

【Abstract】 Objective To investigate the epidemiologic peculiarity,clinical presentations,radiological features and pathological factors of intraparenchymal and/or subcortical meningiomas.Methods The authors retrospectively studied two patients with intraparenchymal meningiomas operated in recent years and reviewed 17 patients with intraparenchymal and/or subcortical meningiomas reported in the literature.Results In the 19 cases,eight patients were male and eleven were female.The male to female ratio was 1:1.38.The age of the 19 cases ranged from 1 to 73 years,and the median age was 17 years.The initial symptoms of the 19 cases were predominantly epilepsies(52.6%),and next to it were headaches(26.3%).Except for two cases due to lack of the data of CT and MRI,seven(41.2%) were cystic meningiomas,twelve(70.6%) displayed peritumoral edema,and three(17.6%) were accompanied with calcification among the other 17 cases of intraparenchymal and/or subcortical meningiomas.Out of the 19 cases,WHO gradeⅠmade up 78.9%(15 cases),WHO grade II 15.8%(three cases)and WHO grade Ⅲ 5.3%(one case).Most of WHO grade I intraparenchymal and/or subcortical meningiomas were fibroblastic,which made up 73.3%.Conclusions Compared with the common meningioma,intraparenchymal and/or subcortical meningioma is more often occurring in male,and at younger age.The initial symptom is predominantly epilepsies.The incidence of cysts and WHO gradeⅡand Ⅲ meningiomas is higher.The most of WHO gradeⅠintraparenchymal and/or subcortical meningiomas were fibroblastic,a sharp different from common meningiomas.更多还原