【摘要】 目的:探讨动脉瘤栓塞联合脑脊液置换术治疗动脉瘤引起的蛛网膜下腔出血(SAH)的疗效及安全性。方法:SAH患者84例,根据患者意愿分成3组,栓塞加置换组26例,给予动脉瘤弹簧圈栓塞+脑脊液置换治疗;栓塞组28例,仅给予动脉瘤弹簧圈栓塞治疗;保守治疗组30例,仅给予一般药物及对症支持治疗。对比3组脑脊液恢复正常时间、颈项强直及头痛持续时间,脑积水发生率及死亡情况。结果:栓塞加置换组的脑脊液恢复正常时间、颈项强直及头痛持续时间均明显短于保守治疗组(P<0.01),短于栓塞组(P<0.05);脑积水发生率低于保守治疗组(P<0.05),与栓塞组差异无统计学意义;栓塞加置换组及栓塞组均无死亡病例,保守治疗组死亡6例。结论:动脉瘤栓塞联合脑脊液置换术治疗动脉瘤引起的SAH安全有效。更多还原

【Abstract】 Objective: To explore the clinical effect of intra-aneurysmal embolization combined with cerebrospinal fluid(CSF) replacement on patients with subarachnoid hemorrhage(SAH).Methods: Eighty-four SAH patients were divided into three groups.Patients in group A(n=26) were treated with intra-aneurysmal embolization combined with CSF replacement;patients in group B(n=28) with embolization alone;and patients in group C(n=30) with conventional medication only.The recovery time of CSF,duration of neck rigidity and headache,rate of hydrocephalus and death rate were analyzed and compared.Results: The recovery time of CSF,duration of neck rigidity and headache in group A were significantly shorter than those in group C(P<0.01) and group B(P<0.05).The incidence rate of hydrocephalus in group A were lower than that in group C(P<0.05).No patients died in group A and B,but six patients died in group C.Conclusion: Intra-aneurysmal embolization combined with CSF replacement is a safe and effective treatment for SAH.更多还原