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曲安奈德联合白芍总苷治疗糜烂型口腔扁平苔藓的疗效观察

Efficacy of Triamcinolone Acetonide Combined with Total Glucosides of Paeony in the Treatment for Erosive Oral Lichen Planus

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【作者】 宋方庆梅健

【Author】 SONG Fang-qing,MEI Jian.Stomatological Department of Shangrao People’s Hospital,Shangrao 334000,China

【机构】 上饶市人民医院口腔科

【摘要】 目的探讨曲安奈德与白芍总苷联合应用治疗糜烂型口腔扁平苔藓的临床疗效。方法随机将80例糜烂型口腔扁平苔藓患者分成2组进行临床研究。治疗组40例,使用曲安奈德与白芍总苷;对照组40例,使用白芍总苷。在治疗后1、3个月按3级疗效标准评定总体疗效,疗效指标为有效率。结果治疗1个月后治疗组和对照组的总有效率分别为72.5%、42.5%,2组差异有统计学意义(χ2=7.366,P<0.01)。治疗3个月后治疗组和对照组的总有效率分别为95.0%、55.0%,2组差异有统计学意义(χ2=17.067,P<0.001)。结论曲安奈德与白芍总苷联合应用治疗糜烂型口腔扁平苔藓有较好的临床疗效。

【Abstract】 Objective To evaluate the efficacy of triamcinolone acetonide combined with total glucosides of paeony in the treatment for erosive oral lichen planus.Methods A total of 80 patients were treated with triamcinolone acetonide combined with total glucosides of paeony(treatment group) or total glucosides of paeony(control group) in a randomized clinical trial.Mucosal lesion extension was assessed using a three-point scale after treatment.The therapeutic parameter was the efficacy rate.Results The efficacy rate of treatment group was significantly higher than that of control group 1,3 month after treatment respectively(P<0.05).Conclusion The results of this study suggest that triamcinolone acetonide combined with total glucosides of paeony is effective in the treatment of erosive oral lichen planus.

  • 【文献出处】 广东牙病防治 ,Journal of Dental Prevention and Treatment , 编辑部邮箱 ,2011年06期
  • 【分类号】R781.5
  • 【被引频次】2
  • 【下载频次】189
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