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双温度响应性新型糖聚合物的合成与表征

Synthesis and Characterization of Novel Multi-temperature Responsive Glycopolymers

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【作者】 李帆裴丹凤石彤非张国

【Author】 LI Fan1,2,PEI Dan-Feng2,SHI Tong-Fei2,ZHANG Guo1(1.Institute of Materials Science and Engineering,Jilin University,Changchun 130023,China; 2.State Key Laboratory of Polymer Physics and Chemistry,Changchun Institute of Applied Chemistry, Chinese Academy of Sciences,Changchun 130022,China)

【机构】 吉林大学材料科学与工程学院中国科学院长春应用化学研究所高分子物理与化学国家重点实验室

【摘要】 <正>目前,对糖聚合物的研究引起了高分子科学及生物医药等领域的广泛关注,特别是具有温度响应性质的糖聚合物,它们可作为新一代的定向输运药物载体和智能生物材料.然而,具有多个温度响应区间的人工合成的糖聚合物尚未见报道.本文采用原子转移自由基聚合法(ATRP),设计

【Abstract】 Since the existence of sugar groups,glycopolymers can mimic the biological functions of glycolipids and glycoproteins.Recent developments in precision polymerization have made it possible to design glycopolymers of controlled structure and chemical composition.Glycopolymers exhibit sophisticated functions have attracted more and more attentions.Novel glycopolymers containing polyelectrolyte were successfully synthesized by atom transfer radical polymerization.The architectures of the glycopolymers were confirmed by 1H NMR and GPC.DLS and zeta-potential tests were also performed to investigate the solution properties of the glycopolymers.We found that the novel glycopolymers exhibit multi-temperature responsive property.

【基金】 国家自然科学基金创新研究群体科学基金(批准号:50621302,51028301)资助
  • 【文献出处】 高等学校化学学报 ,Chemical Journal of Chinese Universities , 编辑部邮箱 ,2011年08期
  • 【分类号】O631.3
  • 【被引频次】2
  • 【下载频次】229
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