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肝硬化患者血钠水平与肝脏储备功能的关系探讨

The relationship of serum sodium levels to liver functional reserve in patients with liver cirrhosis

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【作者】 孙玉珍任敏党新云舒菊娟董薇占国清

【Author】 SUN Yuzhen,REN Min,DANG Xinyun,et al.Department of Infectious Diseases,People’Hospitol,Fang Country 442100,Hubei Province,China

【机构】 湖北省房县人民医院感染病科湖北医药学院附属人民医院肝病研究所

【摘要】 目的探讨血钠水平与失代偿期肝硬化患者肝脏储备功能的关系。方法回顾性分析150例失代偿期肝硬化并发低钠血症患者的临床资料,根据其入院时血钠水平分为轻、中、重度低钠血症,比较3组患者肝肾和凝血功能、Child-Pugh分级、主要并发症和预后。结果血钠水平越低,患者血清总胆红素、尿素氮、肌酐、凝血酶原时间、Child-Pugh评分及主要并发症发生率越高,白蛋白越低(P<0.05或P<0.01),其病死率也越高。结论失代偿期肝硬化患者血钠水平与肝脏储备功能相关。

【Abstract】 Objective To explore the relationship of serum sodium levels to liver functional reserve in patients with decompensated liver cirrhosis.Methods 150 decompensated liver cirrhosis patients with hyponatremia were analyzed retrospectively.The patients were divided into mild,moderate and severe hyponatremia groups according to their serum sodium levels.Results The more severe patients’serum hyponatremia,the higher their serum total bilirubin,urea nitrogen,creatinine,prothrombin time and Child-Pugh scores and the patients with severe hyponatremia had more major complications,and higher mortality.Conclusions The serum sodium levels in patients with decompensated liver cirrhosis reflect liver functional reserve.

  • 【文献出处】 实用肝脏病杂志 ,Journal of Clinical Hepatology , 编辑部邮箱 ,2011年02期
  • 【分类号】R575.2
  • 【被引频次】5
  • 【下载频次】82
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