【摘要】 磁共振成像技术已成为临床医学影像学检查的重要手段,30%以上的磁共振成像诊断需要使用造影剂,因此磁共振成像造影剂也成为一种重要的临床诊断药物。本文简单介绍磁共振成像造影剂的定义、原理和分类,并对当前的研究进展进行了的评述,认为开发具有靶向性、高弛豫效率、使用安全的造影剂是研究的主要方向。更多还原

【Abstract】 Magnetic resonance imaging(MRI) is one of the most useful diagnostic techniques in clinical medicine and more than 30% of all MRI examinations are accompanied by administration of a contrast agent which has become a class of pharmaceuticals.This review presents the principles,characterization and classification,recent developments of MRI contrast agents.The primary direction of such research is to study the MRI contrast agents with organ-selectivity,high relaxivity and safety.更多还原