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住院儿童药疹293例临床分析
Clinical Analysis of Drug Eruption in 293 Hospitalized Children
【摘要】 目的:分析儿童药疹的临床特点,探讨治疗及预防方法。方法:对293例住院儿童药疹的临床特点、药疹类型及致敏药物种类进行回顾性分析。结果:药疹以猩红热样或麻疹样发疹型为主(57.7%),其次为多形红斑型(18.7%)、荨麻疹型(14.7%)、重症药疹(7.2%)。致敏药物主要为抗生素类(79.6%),其次为抗癫痫药(8.5%)和解热镇痛药(7.5%)。结论:抗生素类(主要为青霉素类,其次为头孢菌素类)已成为药疹的主要致敏药物,其次为抗癫痫药和解热镇痛药。
【Abstract】 Objective: To analyze the clinical characteristics of drug eruptions in hospitalized children and approach the methods for cure and prevention.Methods: Two hundred and ninety-three hospitalized children with drug eruptions were evaluated retrospectively and the types of drug eruptions and of the drugs were analyzed.Results: There were mostly scarlet fever cases or measles cases(57.7%),then erythema multiforme cases(18.7%),urticaria cases(14.7%) and severe cases(7.2%).The drug eruptions were mostly caused by antibiotics(79.6%),then anti-epileptic drugs(8.5%) and antipyretic analgesics(7.5%).Conclusions: Antibiotics(the majority being penicillin,the next being cephalosporin) have become the main allergenic drugs,and anti-epileptic drugs and antipyretic analgesics has become the second.
- 【文献出处】 儿科药学杂志 ,Journal of Pediatric Pharmacy , 编辑部邮箱 ,2011年02期
- 【分类号】R758.25
- 【被引频次】6
- 【下载频次】115