【摘要】 目的:探讨3种方法求算药物溶出度Weibull分布参数的结果差别。方法:分别采用计算器、EXCEL和SPSS软件处理药物溶出数据。结果:3种方法计算得到的T50、Td值和Weibull分布参数m值很接近,但参数г和t0间相差较大。结论:药物溶出度Weibull分布参数的计算结果在准确度上SPSS法>EXCEL法>计算器法。更多还原

【Abstract】 Objective: To investigate different results through three methods of solving drug dissolution based on Weibull’s distribution parameter.Method: The data of drug dissolution based on Weibull’s distribution were treated with statistic calculator,Microsoft Excel and SPSS software respectively.Result: T50,Td and m values were close in three methods,but г and t0 values were much different.Conclusion: Data from SPSS have shown highest accurate,EXCEL method was less accurate,statistic calculator was the most unreliable method.更多还原