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妊娠末期重症急性胰腺炎病人血脂代谢的特点和特殊营养支持治疗

The characteristics of lipidemic metabolism and special nutritional treatment of severe acute pancreatitis in pregnancy in the third trimester

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【作者】 孙立群; 李维勤; 耿艳霞; 童智慧; 李宁; 黎介寿;

【Author】 SUN Li-qun,LI Wei-qin,GENG Yan-xia,TONG Zhi-hui,LI Jie-shou (Research Institute of General Surgery,Clinical School of Medical College of Nanjing University/Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing 210002,Jiangsu,China)

【机构】 南京大学医学院临床学院(南京军区南京总医院)解放军普通外科研究所;

【摘要】 目的:分析妊娠末期并发重症急性胰腺炎(SAP)病人的血脂代谢特点,探讨特殊营养支持治疗的效果。方法:回顾性分析我院普通外科收治的妊娠末期并发急性胰腺炎病人共18例。结果:18例病人均存在血脂增高,以三酰甘油水平增高为主。其中符合高脂血症性胰腺炎14例(78%),仅1例有非妊娠期高血脂病史。病人接受特殊营养支持治疗,特点为尽早EN、低脂低热量高蛋白配方、经空肠持续泵入。全部病人对特殊营养支持治疗耐受良好,血脂在1~3 d内即显著下降,产后血脂水平恢复,并维持正常。结论:妊娠末期并发SAP病人存在妊娠相关性血脂代谢紊乱,高三酰甘油血症是引发SAP的重要原因。病人对特殊营养支持治疗耐受良好,血脂水平能迅速有效地控制。

【Abstract】 Objective: To analyze the characteristics of lipidemic metabolism of severe acute pancreatitis in pregnancy in the third trimester and to investigate the effect of special nutritional treatment.Methods: Medical records were reviewed retrospectively for every pregnant woman complicated with severe acute pancreatitis consecutively admitted to our department.Results: Lipidemic metabolic disorders were seen in all patients and severe hypertriglyceridemia was presented in 14 cases.All the patients received special nutritional treatment,which included earlier EN,low-fat as well as low-calorie and high-protein formula and jejunal feeding.Patients tolerated the special nutritional treatment well and their lipidemia decreased significantly in 1-3 days.The lipidemia remained normal after delivery.Conclusion: The main lipidemic metabolism of severe acute pancreatitis in pregnancy in the third trimester was severe hypertriglyceridemia,which was the main cause of severe pancreatitis.The special nutritional treatment was applied well in these patients and the better effect was available.

【基金】 全军“十一五”医药卫生科研基金资助(06Q028)
  • 【文献出处】 肠外与肠内营养 ,Parenteral & Enteral Nutrition , 编辑部邮箱 ,2011年02期
  • 【分类号】R657.51;R714.2
  • 【被引频次】10
  • 【下载频次】309
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