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鬼针草药材质量标准初步研究

Study on quality standard of spanishneedles herb

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【作者】 胡伟陈飞虎吴繁荣钟明媚刘丽萍

【Author】 HU Wei1,2, CHEN Fei-hu2, WU Fang-rong2, ZHONG Ming-mei2, LIU Li-ping1( 1Department of Pharmacy, The Second Hospital of Anhui Medical University, Hefei 230601, China; 2School of Pharmacy, Anhui Medical University, Hefei 230032, China)

【机构】 安徽医科大学第二附属医院药剂科安徽医科大学药学院天然药物化学实验室

【摘要】 目的:建立鬼针草药材的质量标准。方法:以金丝桃苷和鬼针草总黄酮为指标,采用薄层层析法、比色法和高效液相色谱法对采集的鬼针草药材进行质量标准研究。结果:鬼针草药材中金丝桃苷薄层层析结果为阳性,总黄酮含量不少于5.00mg/g,金丝桃苷含量不少于0.03mg/g。结论:本实验方法简便、准确,能有效控制鬼针草药材的质量。

【Abstract】 Objective: To establish the quality standard of spanishneedles herb. Methods: Taking hyperoside and total flavonoids of spanishneedles herb as targets. Quality standard was studied on collected spanishneedles herb by TLC, colorimetric and HPLC. Results: Quality standared was established that TLC of hyperoside should be positive, TFB content should be not lower than 4.00mg/g, hyperoside content should be not lower than 0.03mg/g. Conclusion: The method was simple, accurate and suitable for quality control of spanishneedles herb.

【基金】 国家重大新药创制专项(No.2009ZX09103386);安徽省高校省级自然科学研究项目(No.KJ2010B384);安徽省自然科学基金(No.090413139)~~
  • 【文献出处】 中华中医药杂志 ,China Journal of Traditional Chinese Medicine and Pharmacy , 编辑部邮箱 ,2011年06期
  • 【分类号】R284.1
  • 【被引频次】11
  • 【下载频次】501
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