【摘要】 目的:探讨狭窄性腱鞘炎病理改变及病理分型。方法:狭窄性腱鞘炎标本及正常腱鞘标本行常规HE染色切片,光镜下观察,用S-100蛋白多克隆抗体行免疫组织化学,观察有否软骨细胞存在。结果:病变腱鞘与正常腱鞘标本常规HE染色病理切片对比观察,发现狭窄性腱鞘炎腱鞘血管扩张淤血,组织水肿,滑膜细胞和纤维组织不同程度增生,毛细血管增生形成乳头,不同程度基质黏液样变性和钙盐沉着,无炎性细胞浸润,S-100蛋白阴性。结论:依据临床病情的发展和病理改变特点,将狭窄性腱鞘炎分为3种类型:Ⅰ型(轻微病变型)、Ⅱ型(组织增生型)、Ⅲ型(钙盐沉着型)。更多还原

【Abstract】 Objective: To investigate the pathological changes and types of stenosing tenovaginitis.Methods: Stenosing tenovaginitis and normal tendon sheath specimens were collected for HE staining,and were observed under light microscope.Then the samples were performed immuno histochemistry by s-100 protein to find whether there were chondrocytes.Results: Stenosing tenovaginitis and normal tendon sheath specimens were compared after HE staining.The clinical pathological changes of stenosing tenovaginitis were vasodilatation,tissue edema,synovial cells and fibrous tissue hyperplasia at different degree,capillary hyperplasia and papillary formation,matrix mucoid degeneration and calcium salt precipitation at different degree,and no inflammatory cell infiltration.S-100 protein was negative.Conclusions: The stenosing tenovaginitis can be divided into three types according to the clinical condition and pathological changes.Type I is slight lesion,type II is hyperblastosis,and type III is calcium salt precipitation.更多还原