【摘要】 目的:探讨支架植入对大脑中动脉(MCA)分叉处动脉瘤的血流动力学影响,以及支架对血流动力学因素特别是壁面切应力(WSS)的影响。方法:结合临床影像,基于计算流体力学(CFD)数值模拟方法,采用ANSYS流体力学软件,对单支架治疗1例MCA分叉处动脉瘤行术前、随访时血流动力学数值模拟分析,比较血液流线和WSS在2种情况下的变化。结果:支架植入后血管形态学发生显著变化,动脉瘤消失,MCA血管分叉夹角由196.4°变小为92.5°。WSS在动脉瘤壁的分布变得更均匀,瘤颈处的高壁面压力区域消失。结论:支架植入明显改变动脉瘤和载瘤动脉的局部血流动力学;CFD数值模拟能直观反映动脉瘤的血流动力学特点。更多还原

【Abstract】 Objective To explore the effect of stent implantation on the hemodynamic characteristics of middle cerebral artery(MCA) aneurysm and analyze the effect of stent on hemodynamic factors such as wall shear stress.Methods One patient with wide-neck MCA bifurcation aneurysm was analyzed before operation and during follow-up according to clinical images and using fluid dynamics software(ANSYS software) based on computational fluid dynamics(CFD) numerical simulation methods.The blood streamlines and wall shear stress were compared in both conditions.Results There was significant change in morphology of arteries after stent implantation and the aneurysm was gone.The angle of vascular bifurcation became smaller from 196.4° to 92.5°.The aneurysm disappeared completely.The distribution of wall shear stress on the surface of aneurysm turned uniform after stent implantation.The region of high wall stress value near the neck of aneurysm was disappeared directly.Conclusion Stent implantation can change the partial hemodynamics of aneurysm and parent artery.The numerical simulation of CFD can directly reflect the hemodynamic characteristics of aneurysm.更多还原