【摘要】 目的:探讨改良胃转流术(GBP)治疗2型糖尿病(T2DM)的可行性及疗效。方法:2008年1月～2009年12月期间,我院普外科对住院的20例2型糖尿病患者,实行改良胃转流手术(GBP),观察患者术前、术后空腹血糖(FPG)、餐后2小时血糖(2hPG)、胰岛素抵抗指数(HOMA-IR)、糖化血红蛋白(HbAlc)及体重指数(BMI)变化,术后随访1年。结果:20例手术均成功,术后随防,19例达治愈标准,1例达好转标准,胰岛素抵抗指数(HOMA-IR)、糖化血红蛋白(HbAlc)与手术前相比明显降低;糖尿病相关并发症均有不同程度缓解,1例术后出现吻合口漏,2例出现胃排空障碍,1例出现胃肠功能紊乱,经保守治疗后痊愈。结论:改良胃转流术(GBP)治疗2型糖尿病(T2DM)是有效的、可行的,值得临床推广。更多还原

【Abstract】 Objective:To explore the feasibility and efficacy of treatment for type 2 diabetes mellitus by inproved gastric bypass.Methods:From January 2008 to December 2009,we researched 20 cases of type 2 diabetes mellitus(T2DM)patients,which execute modified by gastric bypass,preoperative and postoperative patients were observed the change a bout fasting plasma glucose(FPG),2-hour plasma glucose(2hPG),insulin resistance index(homa-ir),glycated hemoglobin(HbALc)and body mass index(BMI)and followed-up of 1 year.Results:20 cases were performed successful,19 cases had cured,1 case was reduced the homa-ir and HbAlc were compared with preoperation significantly reduced.Diabetes associated complications changed obviously.one case was stomach appear anastomotic leakage,2 cases were gastric emptying obstacles,1 case appear gastrointestinal dysfunction.Conclusion:we cured them after consenative therapy is effective,feasible,worthing of clinical promotion.更多还原