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不规则抗体阳性结果分析及临床意义

ANALYSIS OF IRREGULAR POSITIVE ANTIBODY AND ITS CLINICAL SIGNIFICANCE

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【作者】 孙波李萍陈增生王海燕谭丽莉

【Author】 SUN Bo,LI Ping,CHEN Zeng-sheng,WANG Haiyan,TAN Lili(Department of Transfusion,The Affiliated Hospital of Qingdao University Medical College,Qingdao 266003,China)

【机构】 青岛大学医学院附属医院输血科青岛市市立医院检验科

【摘要】 目的检测病人血清中红细胞ABO以外的血型系统不规则抗体产生的频率及其特异性,为临床输血安全提供保障。方法应用微柱凝胶方法,对2 000例临床输血病人血清中不规则抗体进行检测,阳性结果者进一步鉴定其特性。结果检测出不规则抗体阳性25例,其中Rh系统12例,MNS系统5例,Duffy系统3例,Kidd系统2例,P系统1例,Lewis系统1例,混合系统1例。结论不规则抗体的产生以Rh系统为主,输血前进行不规则抗体检测具有重要的临床意义。

【Abstract】 Objective To detect the frequency and specificity of irregular antibodies in patients’ serum,and ensure safety of blood transfusion.Methods Using micro-column gel Coombs method,irregular antibodies in 2 000 patients undergoing blood transfusion were detected,for those with a positive report a further assay was conducted for their property.Results Irregular positive antibodies were recorded in 25 cases out of the 2 000 specimens,in which,Rh was 12 cases;MNS,15;Duffy,three;Kidd,two;P,one;Lewis,one;and hybrid system,one.Conclusion The irregular antibodies are mainly of Rh system,a detection of irregular antibodies before transfusion is of considerable clinical significance.

  • 【文献出处】 青岛大学医学院学报 ,Acta Academiae Medicinae Qingdao Universitatis , 编辑部邮箱 ,2011年06期
  • 【分类号】R446.6
  • 【被引频次】1
  • 【下载频次】119
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