【摘要】 目的:探讨多发性骨髓瘤(multiple myeloma,MM)骨髓细胞学诊断和分型以及其他实验室相关指标特征,提高对MM的认识。方法:对32例MM患者的实验室检查相关资料进行回顾性分析。结果:MM患者可引起贫血、血涂片中红细胞的分布异常、红细胞沉降率(ESR)加快、血清球蛋白含量显著增高、白蛋白/球蛋白比值显著降低、蛋白尿等,根据骨髓片中瘤细胞形态可分为浆细胞型、幼浆细胞型、原浆细胞型和网状细胞型。结论:骨髓检查对MM具有特异性诊断价值,血常规检查、血涂片红细胞分布、ESR、血清蛋白测定等对MM的协助诊断具有重要意义,二者结合能够提高MM诊断的准确性,为临床提供可靠依据。更多还原

【Abstract】 Objective:To explore the cytomorphology and other related laboratory features of multiple myeloma(MM).Methods:The bone marrow cell morphology and related laboratory features of 32 patients with MM were retrospectively analyzed.Results:There were many laboratory test results of MM,such as anaemia,abnormal RBC distribution,higher sedimentation rate of red blood cell,remarkable increase of seroglobulin,decrease of albumin/globulin,albuminuria and so on.According to the bone marrow cell morphology,the multiple myeloma could be divided into 4 groups,as plasmocyte MM,proplasmacyte MM,plasmablast MM,and reticulocyte MM.Conclusions:Morphology observation of bone marrow cells is an important method in MM diagnosis,while blood routine examination,RBC distribution in blood smear,blood sedimentation and determination of serum protein also should be recommended.MM can be more exactly diagnosed by the examination of medullary cytology and the related laboratory examinations.更多还原