【摘要】 目的探讨原因不明性不孕症的中医证候特点,为中药治疗原因不明性不孕症提供辨证依据。方法根据不孕症诊断标准,将219例不孕症患者分为研究组(原因不明性不孕症)108例和对照组(配偶不育症导致的不孕症)111例,分析并比较两组中医证候分布特征,采用二项分类Logistic回归分析原因不明性不孕症的危险证候,以及中医证候与年龄的相关性。结果研究组肝郁证、血瘀证、肾虚证积分显著高于对照组(P<0.01);研究组肝郁证、血瘀证、肾虚证比例显著高于对照组(P<0.01),其中肝郁证为最常见证候(69.44%);研究组以复合证候居多,其中肾虚证复合肝郁证、肾虚证复合血瘀证、肝郁证复合血瘀证的比率较高;肝郁证、血瘀证、肾虚证是原因不明性不孕症的危险证候;肾虚证积分与年龄呈正相关。结论肝郁证、肾虚证、血瘀证为原因不明性不孕症的常见证候和危险证候,其中肝郁证分布最广泛,肾虚证具有年龄相关性。更多还原

【Abstract】 Objective To explore the distribution characteristics of traditional Chinese medicine(TCM) syndromes in unidentified infertility,in an attempt to provide a basis for its syndrome differentiation.Methods According to diagnostic criteria of infertility,a total of 219 infertility women were assigned into study group,including 108 cases of unidentified infertility,and control group,including 111 cases of infertility caused by their husbands’ infertility.The distribution characteristics of TCM syndromes were compared between the two groups.The risk TCM syndromes of unidentified infertility were analyzed using binomial Logistic Regression Analysis.The relation of TCM syndromes with ages was analyzed using Pearson Correlation Analysis.Results The scores of liver depression syndrome,blood stasis syndrome,and kidney deficiency syndrome,as well as their proportions in the study group were significantly higher than those in the control group(P<0.01).The liver depression syndrome,especially complicated syndrome,was the most common in the study group.Complicated syndromes were often characterized by kidney deficiency complicated with liver depression,kidney deficiency complicated with blood stasis,and liver depression complicated with blood stasis.The Logistic Regression Analysis showed that liver depression syndrome,kidney deficiency syndrome,and blood stasis syndrome were three risk factors for unidentified infertility.The scores of kidney deficiency syndrome were positively correlated with ages in the study group.Conclusion Liver depression,kidney deficiency,and blood stasis are the common syndromes,and all of them serve as independent risk factors for unidentified infertility.The liver depression syndrome is the most widespread.The kidney deficiency syndrome is closely related with the ages.更多还原