【摘要】 目的观察中成药癫痫宁片作为添加治疗,对癫痫患者发作严重程度的影响。方法采用前瞻性多中心随机对照试验设计,206例癫痫患者在西医抗癫痫治疗基础上,试验组137例用癫痫宁片,对照组69例用癫痫宁安慰剂,用《成人癫痫发作严重程度量表》进行评分及对伴随症状评分。结果在治疗3个月末,用癫痫发作严重程度总分与基线变化差值的协方差分析的比较,试验组与对照组比较有统计学差异(P<0.01)。两组患者治疗前后伴随症状评分比较,不省人事、全身惊厥抽搐、预感、癫狂、胸闷、眩晕等评分差异有统计学意义(P<0.01或P<0.05)。结论癫痫宁片作为添加治疗,对癫痫病的发作严重程度有确切疗效。更多还原

【Abstract】 Objective To observe the influence of Dianxianning Tablet (Herbal patent medicine for epilepsy) as an added medicine on the severity of epileptic paroxysm.Methods By using the prospective multi-centered randomiz-controlled trial design,206 cases were treated with anti-epilepsy drugs,based on which,the experimental group with 137 cases in it was administered Dianxianning Tablet and the control group with 69 cases was given Dianxianning placebo.The Scale of Severity of Epileptic Paroxysm for Adult Patients was applied to score the epileptic paroxysm and accompanied symptoms of the patients.Results By the end of the 3rd month of treatment,the comparison between the total score of epileptic paroxysm and the analysis of covariance of the baseline changing difference showed a statistical difference between the experimental and control groups (P<0.01).The comparison of the scores of accompanied symptoms of the two groups before and after treatment,and scores of loss of consciousness,whole body convulsion,premonition,manic and depression,chest stuffiness,and dizziness showed statistical difference (P<0.01 or P<0.05).Conclusion Dianxianning Tablet,as an added medicine for epilepsy,is effective in relieving the severity of epileptic paroxysm.更多还原