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中医辨证治疗慢性前列腺炎的多中心随机对照临床研究

Multi-centered Randomize-Controlled Clinical Study on the TCM Treatment for Chronic Prostatitis

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【作者】 陈国宏宋竖旗李海松高瞻王传航李兰群刘英山卢建新高筱松刘兵庞然于慧兰杨志强吴玉强杨俊峰张亚强

【Author】 CHEN Guohong1,SONG Shuqi1,LI Haisong2,Gao Zhan3,WANG Chuanhang4,LI Lanqun4,LIU Yingshan1,LU Jianxin1,GAO Xiaosong1,LIU Bing1,PANG Ran1,YU Huilan1,YANG Zhiqiang1,WU Yuqiang1,YANG Junfeng1,ZHANG Yaqiang1(1.Guang’anmen Hospital,China Academy of Chinese Medical Sciences;2.Dongzhimen Hospital,Beijing University of Chinese Medicine;3.Xiyuan Hospital,China Academy of Chinese Medical Sciences;4.China-Japan Friendship Hospital)

【机构】 中国中医科学院广安门医院泌尿外科北京中医药大学东直门医院中国中医科学院西苑医院中日友好医院

【摘要】 目的评价中医辨证方法治疗慢性前列腺炎的临床疗效。方法采用多中心随机对照临床试验研究方法,将符合慢性前列腺炎诊断的患者按1.5∶1∶1的比例随机分为中药组、中西医结合组和西药组。中药组辨证治疗给予中药汤剂,西药组口服阿奇霉素治疗,中西医结合组同时使用以上两种方法治疗。3组疗程均为4周。主要疗效指标为中医证候评分和慢性前列腺炎症状评分(NIH-CPSI),次要疗效指标为最大尿流率、前列腺液(EPS)白细胞数。结果中药组和中西医结合组治疗后中医证候总评分及各分项评分、NIH-CPSI评分及各分项评分均显著下降,尿流率升高、EPS中白细胞数下降,各项指标组内治疗前后比较均有统计学意义(P<0.05或P<0.01)。结论中医辨证治疗慢性前列腺炎有较好的疗效。

【Abstract】 Objective To evaluate the effect of TCM treatment on chronic prostatitis.Methods The multi-centered randomize-controlled clinical study was carried out.The patients meeting the diagnostic criteria were divided into 3 groups in the ratio of 1.5∶1∶1,namely herbal medicine group,integrated herbal and western medicine group,and western medicine group.The herbal medicine group was administered herbal decoction,the western medicine group was given azithromycin,and integrated group was treated with both.The course of treatment was 4 weeks.The primary indexes for therapeutic effect were TCM syndrome scores and the National Institutes of Health chronic prostatitis symptom index(NIH-CPSI),and the secondary indices were maximum flow rate(MFR)and the white blood cell(WBC)count of expressed prostatic secretion(EPS).Results After treatment,the total syndrome score and scores of symptoms,NIH-CPSI score and other scores were significantly reduced in the herbal medicine group and the integrated group,MFR was raised and WBC decreased.All indexes were significantly improved after treatment(P<0.05 or P<0.01).Conclusion The TCM treatment is effective for chronic prostatitis.

【基金】 中国中医科学院优势病种课题项目(CACMS05Y0016)
  • 【文献出处】 中医杂志 ,Journal of Traditional Chinese Medicine , 编辑部邮箱 ,2010年05期
  • 【分类号】R277.5
  • 【被引频次】24
  • 【下载频次】714
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