【摘要】 目的探讨鞘内使用万古霉素治疗颅内感染的临床疗效。方法对25例颅内感染患者采用万古霉素,每次20.0mg用生理盐水稀释至5.0ml,鞘内注射后夹闭2 h再开放引流,1次/d,直至患者体温及脑脊液中白细胞正常。结果治愈20例,好转4例,死亡1例,病死率4.0%,预后良好率达96.0%。结论万古霉素鞘内注射治疗颅内感染能取得满意疗效。更多还原

【Abstract】 Objective To explore the clinical therapeuric effect of the intrathecal injection with vancomycin for intrcranial infection.Methods Twenty-five patients with intracranial infection were treated by 20.0 mg vancomycin diluted with 5.0 ml sodium chloride injection into lumber tube by its the external drainage once a day.The drainage tube had two hours occlusion after drug injection.When the temperature and white blood cell in cerebrospinal fluid of patients were normal the drainage tubes were removed.Results Twenty cases were cured, four cases had favourable outcome.One case was dead(4.0%).Conclusion The treatment of intrathecal injection with vancomycin for patient with intracranial infection could be satisfactory.更多还原