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1036例静脉吸毒者肝功能及乙肝、丙肝、梅毒、艾滋病感染血清标志物调查分析

Analysis of liver function,HBV,HCV,Syphilis and HIV infection serum marker in 1036 intravenous drug abusers

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【作者】 吴统健孙林渥郭永炼包炳辉谢加奖黄建伟

【Author】 WU Tong-jian1,SUN Lin-wo1,GUO Yong-lian1,BAO Bing-hui1,XIE Jia-jiang1 HUANG Jian-wei 2(1 Xianyue Hospital Labortory of Xiamen,Xianmen,361012;2 Disease prevent and control center of Xiamen,361021)

【机构】 仙岳医院检验科厦门疾病预防控制中心

【摘要】 目的:了解厦门地区静脉吸毒者传染病的感染状况及相关因素,为更有效地预防和控制吸毒人群传染病的感染与传播提供依据。方法:同时收集静脉吸毒者血清1036份和正常人群血清标本874份,进行肝功能、乙肝表面抗原、丙肝抗体、梅毒抗体、艾滋病抗体检测,作对比分析。结果:1036例静脉吸毒者血清标本中,肝功能异常率30.5%;乙肝表面抗原阳性率17.86%;丙肝抗体阳性率55.3%;梅毒抗体阳性率4.5%;艾滋病抗体0.68%;对照实验:874例正常人群,肝功能异常率5.1%,乙肝表面抗原阳性率10.18%,丙肝抗体阳性率2.7%,梅毒抗体阳性率0.8%,艾滋病抗体阳性率为零。两组结果对照的差异性,具有统计学意义。结论:静脉吸毒者肝功能、乙肝、丙肝、梅毒、艾滋病血清学标志物感染率明显高于正常人群,是传染病感染与传播的高危人群。吸毒者的吸毒模式和行为模式是各项传染病感染与传播的主要因素。

【Abstract】 Objective:To understand the situation and correlated factor of liver function and epidemic infected that HBV、HCV、syphilis and HIV on 1036 intravenous drug abusers(IVDAS)in Xiamen area.Methods:The collected 1036 example of Application of biochemistry test that liver function and application of ELISA that HbsAg/anti-HCV/antHIV1+2/TP(RPR positive)from IVDAS,874 serum example make contrast test from normal crowd.Results:Among 1036 IVDAS,316(30.5%)were liver function unusual,185(17.86%)of HbsAg positive,573(55.3%)of anti-HCV positive,47(4.5%)of RPR positive,7(0.68%)anti-HIV1+2 positive,Contrast experiment showed that 874 serum specimens from normal crowd 45(5.1%) were liver function unusual,89(10.18%)of HbsAg positive,24(2.75%)anti-HCV positive,13(1.49%)of RPR/TP positive,The anti-HIV1+2 all negative.There are significant difference between two samples.Conclusion:The IVDAS are easy to be infected by HBV、HCV、syphilis and HIV.Drug use and sex behavior of IVDAS are important factor.

  • 【文献出处】 中国药物滥用防治杂志 ,Chinese Journal of Drug Abuse Prevention and Treatment , 编辑部邮箱 ,2010年03期
  • 【分类号】R749.64;R181.3
  • 【被引频次】9
  • 【下载频次】159
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