【摘要】 目的:观察复方崩大碗灌肠剂各个剂量组对腺嘌呤致大鼠慢性肾功能衰竭(CRF)模型的影响,并与尿毒清颗粒组、正常组、模型组比较,观察其对慢性肾功能衰竭(CRF)的作用。方法:用含0.5%的腺嘌呤(Ade-nine,Ade)饲料喂养大鼠建立大鼠CRF模型,各组给药治疗27天后,采集血液、尿液标本观察大鼠血尿素氮(BUN)、肌酐(Scr)和24h尿量、尿蛋白定量(UTP)水平的变化。结果:与模型对照组相比,复方崩大碗灌肠剂各个剂量均能不同程度降低血BUN、Scr、UTP水平升高。结论:复方崩大碗灌肠剂在改善慢性肾功能衰竭(CRF)、氮质血症早期和延缓肾功能恶化方面有较好的保护作用。更多还原

【Abstract】 Objective:To observe the effects of Bengdawan compound enemas to improving the chronic renal failure(CRF)Rat. Methods:The rat model of chronic renal insufficiency was made by feeding 0.5% adenine forage,after treat the rats 27 days ago,collect the blood and urine to observe the change of the blood biochemical indexes,24h-urine volume and 24h-urine proteinion.Results:Compared with the model group,the Bengdawan Compound enemas obviousl reduced the BUN Scr UTP level to increase. Conclusion:The Bengdawan compound enemas has the potential protection against the chronic renal failure earlier azotemia and delay renal aggrav in rats.更多还原