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老年急性白血病化疗后医院感染及抗感染治疗分析

Hospital infection after chemotherapy in patients with old acute leukemia and its anti-infection therapy

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【作者】 谢瑜谭琳吴迪

【Author】 XIE Yu, TAN Lin,WU Di.First Affiliated Hospital of Kunming Medical College,Kunming 650032,China

【机构】 昆明医学院第一附属医院

【摘要】 目的探讨老年急性白血病化疗后医院感染的易感因素及治疗对策。方法对86例老年急性白血病患者住院化疗后医院感染发生及治疗情况进行回顾性分析。结果 86例患者中发生化疗后医院感染76例,经治疗后46例感染得到控制,30例患者感染未控制、病情进展,发生多脏器功能衰竭并最终导致死亡。中性粒细胞计数降低、未完全缓解是医院感染的主要易感因素。结论抗生素及粒细胞集落刺激因子的合理应用,可改善老年急性白血病患者化疗后感染的发生率及预后。

【Abstract】 Objective To investigate the risk factors and therapeutic tactics of hospital infection after chemotherapy in patients with old acute leukemia(AL).Methods 86 patients with old AL were analyzed retrospectively about hospital infection and their therapy after chemotherapy.Results 76 patients were infecting in the 86 cases.46 patients’s condition had been controled after antibiotic therapy,30 of them died of MODS.The lower ANC and no complete remission were the primary risk factors that lead to infection.Conclusion Combining antibiotic therapy and G-CSF could reduced the infection rate and its prognosis.

【关键词】 急性白血病老年化疗后感染治疗
【Key words】 Acute leukemiaOldInfection after chemotherapyTherapy
  • 【文献出处】 中国医学创新 ,Medical Innovation of China , 编辑部邮箱 ,2010年34期
  • 【分类号】R733.71
  • 【被引频次】4
  • 【下载频次】21
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