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老年吸入性肺炎患者动态监测血清超敏C反应蛋白的临床意义
Clinical value of high-sensitivity C-reactive protein in the treatment of the elderly with aspiration pneumonia
【摘要】 目的探讨动态监测血清超敏C反应蛋白(hs-CRP)水平在老年吸入性肺炎患者诊治中的临床价值。方法对47例老年吸入性肺炎患者于确诊当日、第3天和第7天后静脉抽取血标本,测定血清hs-CRP水平,并结合患者的病情变化和转归情况,进行分析和比较。结果本组47例老年吸入性肺炎患者经相应治疗后,治愈或明显好转34例,死亡13例。病情危重组患者的第3天和第7天的血清hs-CRP水平较病情较轻组均明显升高,差异具有统计学意义;第3天和第7天血清hs-CRP水平与患者的临床肺部感染评分均呈正相关。同时,治愈或明显好转组患者的第1天、第3天和第7天的血清hs-CRP水平均较死亡组明显升高,差异具有统计学意义。结论血清hs-CRP水平变化与老年吸入性肺炎患者的病情演变具有相关性,动态监测血清hs-CRP水平能有效反映患者的病情严重程度和进展情况。
【Abstract】 Objective To explore the clinical value of high-sensitivity C-reactive protein (hs-CRP) in the treatment of the elderly with aspiration pneumonia. Methods Blood sample from venous were collected in 47 patients with aspiration pneumonia on admission,3rd and 7th d after treatment. The level of Hs-CRP was measured and compared according to the condition changes. Results After treatment,34 cases were apparently improved while 13 died. Hs-CRP in the severe patients on 3rd and 7th d was higher than the mild group. Meanwhile,the level of Hs-CRP in survivors markedly elevated than the death. Conclusions Hs-CRP level is correlated with condition changes in the elderly with aspiration pneumonia. Dynamic observation on Hs-CRP level can effectively reflect the disease severity and progress changes.
【Key words】 Aspiration pneumonia; Aged; High-sensitivity C-reactive protein; Infection;
- 【文献出处】 中华危重症医学杂志(电子版) ,Chinese Journal of Critical Care Medicine(Electronic Edition) , 编辑部邮箱 ,2010年03期
- 【分类号】R563.1
- 【被引频次】14
- 【下载频次】124