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旋光法测定复方达克罗宁薄荷脑润肤止痒水中薄荷脑的含量
Menthol Content In the Compound Dyclonine menthol antipruritic emollients water with Optical Rotation
【摘要】 目的建立复方达克罗宁薄荷脑润肤止痒水中薄荷脑的含量测定方法。方法采用旋光法直接测定薄荷脑的含量。结果薄荷脑在1.13~5.65mg/ml浓度范围内,旋光度与浓度呈良好线性关系,回归方程α=86.46C+0.012,r=0.9998,平均回收率为99.6%。结论本法操作简便,准确性好,适合复方达克罗宁薄荷脑润肤止痒水中薄荷脑的含量测定。
【Abstract】 Objective To established the method for the determination of menthol in the Compound Dyclonine menthol antipruritic emollients water.Methods Optical Rotation was used to determine the content of menthol.Results The test of menthol was linear within the range of 1.13 ~ 5.65 mg/ml,r = 0.9998.The average recovery was 99.6% .Conclusion The methods are simple and accurate.And the methods are suitable to determine the menthol content in the Compound Dyclonine menthol antipruritic emollients water.
【关键词】 复方达克罗宁薄荷脑润肤止痒水;
薄荷脑;
旋光法;
含量测定;
【Key words】 Compound Dyclonine menthol antipruritic emollients water; Menthol; Optical Rotation; Content determination;
【Key words】 Compound Dyclonine menthol antipruritic emollients water; Menthol; Optical Rotation; Content determination;
【基金】 深圳市科技计划项目(项目编号:200902144)
- 【文献出处】 中国现代药物应用 ,Chinese Journal of Modern Drug Application , 编辑部邮箱 ,2010年13期
- 【分类号】R927
- 【被引频次】3
- 【下载频次】120