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血清β-HCG及孕酮检测在异位妊娠早期诊断中的价值

The value of serum β-HCG and progesterone in the early diagnosis of ectopic pregnancy

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【作者】 蔡紫薇杨国奋

【Author】 CAI Zi-wei,YANG Guo-fen.Department of Obstetrics and Gynecology,Meilong People’s Hospital of Haifeng County,Haifeng 516400,China

【机构】 广东省汕尾市海丰县梅陇人民医院妇产科中山大学附属第一医院妇产科

【摘要】 目的探讨血清β-人绒毛膜促性激素(β-HCG)及孕酮检测在异位妊娠早期诊断中的价值。方法分别检测46例异位妊娠患者和48例同期宫内早期妊娠妇女的血清β-HCG和孕酮的浓度值。结果异位妊娠组血清β-HCG和孕酮低于宫内妊娠组,差异有统计学意义(P<0.01)。以孕酮<15ng/ml作为诊断异位妊娠的临界点,其敏感度为91.3%,特异度为93.75%,阳性预测值为93.3%,阴性预测值为91.8%。结论血清β-HCG与孕酮联合测定可提高异位妊娠早期诊断的敏感性和特异性。

【Abstract】 Objective To explore the value of serum β-HCG and progesterone in the early diagnosis of ectopic pregnancy.Methods Serum β-HCG and progesterone were assayed of 46 cases were suspected to be ectopic pregnancy and 48 women who were intrauterine gestation.Results The serum β-HCG and progesterone value in ectopic pregnancy group were significantly lower than those in intrauterine gestation group(P<0.01).When the cut-off point of progesterone was<15ng/ml,the sensitivity and the specificity were 91.3% and 93.75% respectively,and the positive predictive value and negative predictive value were 93.3% and 91.8% respectively in the diagnosis of ectopic pregnancy.Conclusion Combined assaying Serum β-HCG with progesterone can enhance the sensitivity and the specificity in the diagnosis of ectopic pregnancy.

  • 【文献出处】 中国现代药物应用 ,Chinese Journal of Modern Drug Application , 编辑部邮箱 ,2010年01期
  • 【分类号】R714.22
  • 【被引频次】5
  • 【下载频次】172
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