【摘要】 目的:了解甘肃省细菌性痢疾发病规律,及志贺菌的病原学和药敏特点,为细菌性痢疾的防制提供科学依据。方法:对甘肃省报告和监测的细菌性痢疾病例进行流行病学分析,按《全国细菌性痢疾监测方案》提供的方法对菌株进行检测。结果:2005年-2009年细菌性痢疾年均发病率63.87/10万,0岁(婴儿)组年均发病率最高469.64/10万,但检测阳性率较其他年龄组最低12.41%。对571株阳性志贺菌株分型,福氏志贺菌339株,宋内氏230株。阿莫西林、氨苄西林、四环素、利福平的多重耐药率94.62%。结论:全省2005年-2009年细菌性痢疾发病呈平缓下降趋势,但流行菌型有所变化,宋内氏菌比例增加,婴儿组病例诊断准确性不高,志贺菌耐药性日趋严重,对菌痢的防控工作提出了新的挑战。更多还原

【Abstract】 Objective:To understand the onset rules,etiological characteristics and antimicrobial susceptibility of bacillary dysentery in Gansu province,we can provide scientific basis for the prevention and control.Methods: By the epidemiological methods to analyze the cases of basillary dysentery which were collected through China Disease Reporting Information System and National Sentinel Surveillance Site on bacillary dysentery in Gansu province,and tested bacterial strains according to national protocol of shigellosis surveillance.Results: The bacillary annual average incidence rate was 63.87/100000 from 2005 to 2009.The annual average incidence rate of infant was 469.64/100000.But the detection rate of infant was 12.41%,less than that of other age group.In the positive Shigella which were 571 strains,339 strains belonged to S.flexneri and 230 strains belonged to S.sonnei,but only 2 stains of S.dysenteriae.The annual average drug resistence rate was 94.62% to amoxicillin,ampicillin,tetracycline,rifampicin.Conclusion: The incidence rate of bacillary descended gently from 2005 to 2009,but because continuous variety of bacterial type,increasing of S.sinnei,low diagnostic accuracy of infant and ascending drug resistence,we should be confronted with new challenge to the prevention and control of dysentery.更多还原