【摘要】 目的探讨胺碘酮片与门冬氨酸钾镁片联用治疗阵发性心房颤动(房颤)的有效性和安全性。方法78例发作频繁的阵发性房颤患者,男41例,女37例,平均年龄(57.8±11.2)岁。随机分为研究组和对照组,前者同时应用胺碘酮片和门冬氨酸钾镁片,后者仅服用胺碘酮片。随访时间为1年。结果研究组治疗1年的总有效率为77.5%(31/40),显著高于对照组治疗1年的总有效率52.6%(20/38),P<0.05。结论和单纯应用胺碘酮片比较,胺碘酮片和门冬氨酸钾镁片联用能够显著提高预防阵发性房颤发作的效果,同时并未增加严重不良反应。更多还原

【Abstract】 Objective To investigate the efficacy and safety of combination with amiodarone and panangin in the treatment of patientswith paroxysmal atrial fibrillation (PAF).Methods Seventy-eight patients[male 41,age (57.8±11.2) years] with PAF and indi-cations for lipid-lowering therapy were assigned into amiodarone plus panangin group (group 1,n=40) aswell as amiodarone alonegroup (group 2,n=38) randomly.The follow-up duration for every patientwas one year.Results The overall efficacy rate in group 1was 77.5% (31/40),which was significantly higher than that in group 2 [52.6% (20/38),P<0.05].Conclusion Compared with amiodarone alone,amiodarone combined with panangin had a better efficacy aswell as a similar safety.更多还原