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蒙药荜茇三味胶囊提取工艺的研究

Extraction craft research of Mongolian drug piperine three taste capsule

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【作者】 王烈群那顺朝克图张欣刘宏婧白广翠

【Author】 Wang liequn Nashun Chaoketu Zhang Xin Liu Hongjing Bai guangcui (Inner Mongolian medical college pharmacy specialty,Huhhot 010059)

【机构】 内蒙古医学院药学院

【摘要】 目的:优选蒙药荜茇三味胶囊的提取条件。方法:采取正交实验法,用高效液相色谱法,以测定提取物中胡椒碱的含量为指标,考察乙醇浓度(A)、乙醇用量(B)、提取时间(C)、提取次数(D)等4个条件对提取效果的影响;进行四因素三水平试验。结果:实验设计因素中乙醇用量的影响最为显著。结论:荜茇三味胶囊的最佳提取工艺条件为A1B1C1D2,即每次加入药材6倍量的65%乙醇,提取2次,每次提取60min。

【Abstract】 Goal: The option of Mongolian drug piperine three taste capsule extraction condition.Method: Adopt the orthogonal experiment method, with the high performence hquid chromatography,determine the content of piperine in the extraction as the target, inspect four conditions which influence the effect, including the ethyl alcohol density (A) , ethyl alcohol amount used (B) , extraction time ( C) , extraction number of times ( D) ; Carry on four factor three level experiments. Finally: the best extraction technological condition of the Mongolian drug piperine three taste is A1B1C1D1, namely: join 6 times as 65% ethyl alcohol as the raw material for medicine each time, backflow 1 time, each time needs 60min.Conclusion:This method is feasible.

  • 【文献出处】 中国民族医药杂志 ,Journal of Medicine & Pharmacy of Chinese Minorities , 编辑部邮箱 ,2010年02期
  • 【分类号】R291.2
  • 【被引频次】4
  • 【下载频次】106
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