【摘要】 目的:观察立止血联合垂体后叶素治疗肺结核咯血的临床疗效。方法:将128例肺结核咯血病例随机分成两组,均给予小剂量垂体后叶素2U/h,静滴8～12h,每天1次,出血停止后停用。在此基础上,治疗组应用立止血1kU肌注,1kU静推,每日1次,连用3d。观察两组的疗效及药物副作用。结果:治疗组有效率92.2%,对照组有效率62.5%;治疗组止血时间(1.54±0.65)d,明显短于对照组(2.31±0.91)d,两组比较有非常显著差异(P<0.01)。治疗组未见明显不良反应,对照组不良反应发生率为40.62%。结论:立止血联合垂体后叶素治疗肺结核咯血是一种安全可行、高效迅速、使用方便的止血方法。更多还原

【Abstract】 Objective:To observe the clinical curative effect of Replilase together with posterior pituitary on hemoptysis of pulmonary tuberculosis.Methods:128 cases of hemoptysis of pulmonary tuberculosis randomly divided into groups:treatment group(n=64),which be treated with Replilase(1kU im,1kU iv,qd,continually for 3d,until the hemoptysis stopped) and posterior pituitary(2U/h,ivgtt,8～12h,qd) and the contralled group(n=64) which be only treated with posterior pituitary(2U/h,ivgtt,8～12h,qd,until the hemoptysis stopped),assessing the curative and side effects.Results:Effective rate was 92.2% for therapy cases which has few adverse effects,and 62.5% for contralled group.The mean time to hemostasis of effective rate was obviously shorter than contralled group,there were statistical differences between two groups(P<0.01).Conclusion:It was safe,effective and convenient to use Replilase together with posterior pituitary on hemoptysis of pulmonary tuberculosis.更多还原