【摘要】 研究了以山梨醇和月桂酸为原料,在固定化脂肪酶的催化下合成山梨醇月桂酸酯的反应。通过考查原料配比、酶的用量、溶剂(丙酮)的用量、反应温度及时间等因素对反应的影响,确定了最佳反应条件为:原料配比山梨醇∶月桂酸为2.0∶1(物质的量比),反应的溶剂为丙酮,丙酮用量为10 mL/mmol月桂酸,固定化脂肪酶的用量为0.24 g/mmol月桂酸,在60℃下反应72 h,月桂酸的转化率可达到98.2%。当山梨醇月桂酸酯的质量分数为0.06%时,产物的表面张力约为41.5×10-5 N/m。更多还原

【Abstract】 Sorbitol laurate was synthesized from sorbitol and laurel acid in the presence of immobilized lipase.The influencing factors of the reaction,such as formula ratio of raw material,enzyme dosage,solvent dosage,reaction temperature and time,were investigated.Results: The conversion rate of laurel acid reaches 98.2% under such conditions as Novozym 435 lipase dosage 0.24 g/mmol laurel acid,the molar ratio of sorbitol to laurel acid 2.0∶1,solvent dosage acetone 10 mL/mmol laurel acid,and reflux reaction at 60 ℃ for 72 h.The surface tension of the aqueous solution of sorbitol laurate at concentration 0.06% is about 41.5×10-5N/m.更多还原