【摘要】 目的:检测糖尿病性视网膜病变(DR)患者动脉硬化程度,观察动脉硬化检测值是否可作为中药治疗早期介入防治DR的参考指标。方法:对125例DR患者进行动脉硬化检测,以动脉硬化程度为指标将DR患者分为正常、轻度、中度、重度四组,另选择同期门诊患者中无眠底病变者61例为对照组,比较DR各组中药治疗前后肱踝脉搏波传导速度(baPWV),以及视力、视网膜出血、硬性渗出及棉絮斑改变情况,并与对照组比较。结果:DR患者动脉硬化程度与对照组比较,差异有统计学意义(P<0.05);DR患者经中药治疗后视力与眼底病变均有改善,动脉硬化轻、中度组疗效优于重度组,差异有统计学意义(P<0.05)。结论:baPWV值能反映视网膜动脉的功能状态,或可作为DR早期中药治疗介入时机的参考指标。更多还原

【Abstract】 Objective:To investigate atherosclerosis as an indicator for early Chinese medical intervention for diabetic retinopathy(DR).Methods:A total of 125 DR patients from our clinic were detected for atheroclerosis.The degree of atheroclerosis was divided into mild,medium,and severe groups.Another 61 patients without DR from the clinic during the corresponding period served as controls.Each group was treated with Chinese medicine and the brachial-ankle pulse wave velocity(baPWV),vision,and eyeground pathological changes.were compared before and after treatment and between the DR and the control groups.Results:Significant difference in the degree of atherosclerosis was noted between the DR and the control groups(P<0.05).After Chinese medical intervention,the vision and eyeground pathological changes were improved in all DR groups,with better effects in mild and medium groups(P<0.05).Conclusion:baPWV value reflects the function of artery in fundus and may be used as an indicator for early Chinese medical intervention.更多还原