【摘要】 收集2005-2009年河南省输入性恶性疟疫情报告资料进行分析。2005-2009年共报告输入性恶性疟84例,男女比例为20:1,患者平均年龄为(34±11)岁,其中非洲回国人员75例(占89.3%)。2008年(24例)和2009年(32例)的病例数高于2005-2007年(9～10例)。发病风险居前3位的为农民(34例)、工人(17例)和干部(13例),三者占全部病例的76.2%。全年均有病例报告,其中流行季节的6、7月发病较高(37例,占44.0%)。患者均有恶性疟疫区居留史,以发热为首发症状。从发病到确诊的平均天数为(5.9±8.6)d,仅21.4%(18/84)的患者24 h内确诊。实验室确诊病例72例(占85.7%)。县级医疗单位报告17例(占22.1%)。经复方青蒿素类药物治疗后83例痊愈,1例死于重症脑型疟。提示相关单位需采取有效措施控制上升的输入性恶性疟疫情。更多还原

【Abstract】 Imported falciparum malaria data of Henan Province in 2005-2009 were collected and statistically analyzed by using Microsoft Office Excel 2003.A total of 84 imported falciparum malaria cases with one death were reported during 2005-2009.The ratio of males to females was 20:1(80/4).The average age was (34±11)years old. Seventy-five patients returned from Africa,occupying 89.3%.The number of annual cases reported in 2008 (24 cases) and 2009 (32 cases)was higher thanthat in 2005-2007(9-10 cases).The top three high-risk populations were farmers (34 cases),workers (17 cases)and the cadre (13 cases),accounted for 76.2% of all cases.The cases were reported every month,of which 37 cases(44.0%)were reported in June and July.All cases had a history of prior residence in falciparum malaria endemic area,and the initial symptom was fever.The average interval from symptom appearing to diagnosis was (5.9±8.6)d,only 21.4% (18/84)of the patients was diagnosed within 24h.There were 72 laboratoryconfirmed cases(85.7%).Seventeen cases (22.1%)were reported by county level medical treatment units.A total of 83 cases recovered with the treatment of artemisinin-based combination drugs.One case died with serious cerebral malaria. Effective measures should be carried to control the increasing trend of imported falciparum malaria.更多还原