【摘要】 目的探讨医院假丝酵母菌属医院感染的菌种分布与耐药性,为临床合理用药提供试验依据。方法假丝酵母菌属的分离、鉴定按《全国临床检验操作规程》进行,药敏敏感试验采用K-B法。结果 189株假丝酵母菌属中,白色假丝酵母菌居第1位,占57.2%;热带假丝酵母菌第2位,占18.5%;假丝酵母菌属对氟康唑、克霉唑、伊曲康唑等常用抗真菌药物的耐药率为7.4%～18.2%;对两性霉素B、制霉菌素敏感率为100.0%。结论临床对疑为真菌医院感染患者,务必进行病原学培养,以早期发现病原性真菌和选择有效的抗真菌药物控制感染。更多还原

【Abstract】 OBJECTIVE To study the flora distribution and drug resistance in nosocomial infection with Candida in order to provide the reference for reasonable use of antifungal agents.METHODS C.andida were isolated and identified according to the National Clinical Laboratory Operation Regulation.The susceptibility test was performed by K-B method.RESULTS Among 189 strains of C.andida,C.albicans ranked the top,accounted for 57.2%.Then C.tropicalis ranked the second,accounted for 18.5%.The drug resistance rates to commonly used antifungal drugs,such as fluconazole,clotrimazole and itraconazole,were 7.4% to 18.2%.The drug susceptibility rates to amphotericin B and nystatin were 100.0%.CONCLUSION With regard to the cases of nosocomial infections with C.andida suspected clinically,the etiological detection should be performed in order to discover earlier pathogenic fungis and select the effective antifungal agents.更多还原