【摘要】 纳米药物晶体可解决多数难溶性药物的溶解度和溶出度问题,近年来成为难溶性药物给药系统研究的热点之一。本文着重综述了纳米药物晶体的制备技术,如沉淀法、分散法、乳化法和微乳化法、超临界流体结晶法等的研究进展。更多还原

【Abstract】 The solubility and dissolution problems of the majority of the slightly soluble drugs can be improved by preparing drug nanocrystals.Therefore drug nanocrystals have become one of the focal points of drug delivery systems.Based on recent literatures at home and abroad,this paper emphasizes on the progress of the preparation techniques of drug nanocrystals,such as precipitation method,dispersion method,emulsif ication and microemulsif ication,supercritical fluid crystallization,etc.更多还原