【摘要】 目的:研究良性前列腺增生症细胞因子水平与中药干预的影响。方法:采用随机病例对照设治疗组(A组),对照组(B组)及健康组(C组)。A组用前列宁汤,每日1剂,分2次口服。B组用前列康3片/次,每日3次口服,2组疗程均8周。结果:治疗前AB组TNF-α,IL-17/IL-10,IL-4与C组比明显失调(P<0.01)。治疗后A组TNF-α,IL-17明显降低,IL-10,IL-4明显提高,与治疗前比有显著性差异(P<0.01)。与B组比有显著性差异(P<0.01)。但仍然达不到C组水平。结论:前列宁汤能有效调节前炎症细胞因子与抗炎症细胞因子的水平,为临床诊断与治疗BPH提供科学实验依据。更多还原

【Abstract】 Objective: To make a study of the influence of the intervene of traditional Chinese medicine on cytokine level in benign prostatic hyperplasia.Method: The patients were divided into treatment group(group A),control group(group B) and healthy group(group C) with the randomly compared researching method.Group A were given Qianliening Tang(QLNT),daily potion,two times a day.Group B were given Qianliekang,three times a day,three pills each time.The course of both treatment lasted for 8 weeks.Result: Before treatment,TNF-α,IL-17/IL-10,IL-4 in group A and B are obviously out of order compared with group C(P<0.01).After the treatment,TNF-α,IL-17 in group A decreased dramatically and IL-10,IL-4 increased,which shows great differences compared with those before treatment and with group B(P<0.01),but still can’t reach to group C level.Conclusion: Qian liening Tang can efficiently regulate the level of suppressive inflammatory cytokines and proinflammatory cytokines.It provides scientific experimental basis for clinical diagnosis and treatment of the disease.更多还原