【摘要】 目的:评价电针联合活血化瘀中药、康复训练综合方案治疗脑梗死的临床疗效。方法:采用多中心随机对照研究方法,将320例患者分为电针+中药+康复训练组(A组)、电针+康复训练组(B组)、中药+康复训练组(C组)、单纯康复训练组(D组),每组80例。其中针刺取穴以两组穴位交替:①血管舒缩区、肩髃、髀关、合谷、太冲,②运动区、曲池、阳陵泉、肾俞,采用电针疗法;活血化瘀中药采用香丹注射液20 mL加5%葡萄糖250 mL或0.9%氯化钠注射液250 mL,静脉点注,每天1次;康复训练由专业康复师进行实施。各组根据所采取的治疗方案进行相应的治疗。以发病后3个月死亡/残障率作为指标进行疗效评价,对数据进行意向性分析(ITT分析)。结果:4组发病后3个月死亡/残障率分别为:A组17.5%(14/80),B组22.5%(18/80),C组40.0%(32/80),D组31.3%(25/80)。A组疗效最佳,与C组、D组比较差异有统计学意义(均P<0.05),未发现不良事件报道。结论:电针、活血化瘀中药、康复训练三者综合应用,是临床治疗脑梗死的较佳手段。更多还原

【Abstract】 Objective To evaluate the therapeutic effect of comprehensive therapeutic protocol of electroacupuncture combined with active-blood-and-dissolve-stasis herbs and rehabilitation training for cerebral infarction.Methods A multi-center randomized controlled trial was done,three hundred and twenty cases were divided into four groups: electroacupuncture combined with active-blood and dissolve-stasis herbs and rehabilitation training group(group A), electroacupuncture combined with rehabilitation training group(group B),herbs combined with rehabilitation training group(group C) and rehabilitation training group(group D),80 cases in each group.The following two groups of acupoints were used alternatively in electroacupuncture treatment:the first group including Vasomotor Area,Jianyu(LI 15),Biguan(ST 31),Hegu(LI 4) and Taichong(LR 3);the second group including Motor Area,Quchi(LI 11),Yanglingquan(GB 34) and Shenshu(BL 23).20 mL Xiangdan injection and 250 mL 5% glucose injection or 250 mL 0.9%sodium chloride injection were used by intravenous drip in herbs treatment once a day. The rehabilitation training was performed by the professional physical therapist.Each group was treated with corresponding treatment protocol.The therapeutic effect was evaluated by index of the mortality or disability rate 3 months after the onset of disease.The intention to treat analysis(ITT) was used in data.Results The mortality or handicap rate 3 months after the onset of disease of four groups were 17.5%(14/80) in group A,22.5%(18/80) in group B,40.0%(32/80) in group C,and 31.3%(25/80) in group D,respectively.The group A has a best therapeutic effect(vs group C,group D, both P<0.05),and there was no adverse event.Conclusion The combined application of electroacupuncture,active-blood and dissolve-stasis herbs and rehabilitation training is a better treatment for cerebral infarction in clinic.更多还原